CARL: February 2012

Tuesday, February 28, 2012

TEAR'S

Tears are secretions that clean and lubricate the eyes There are three very basic types of tears:

In healthy mammalian eyes, the cornea is continually kept wet and nourished by basal tears. They lubricate the eye, and help to keep it clear of dust. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium. Some of the substances in lacrimal fluid (such as lysozyme) fight against bacterial infection as a part of the immune system. Lysozyme does this by dissolving a layer in the outer coating, called peptidoglycan, of certain bacteria. It is a typical body fluid with a salt content similar to blood plasma. Usually, in a 24-hour period, 0.75 to 1.1 grams (0.03–0.04 ounce avoirdupois) of tears is secreted; this rate slows with age.^[1]

Strong emotions such as sorrow or elation, awe, pleasure, irritation of the eyes, laughing, and yawning may lead to an increased production of tears, or crying.

The second type of tears results from irritation of the eye by foreign particles, or from the presence of irritant substances such as onion vapors, tear gas, or pepper spray in the eye's environment, including the cornea, conjunctiva, or nasal mucosa. It can also occur with bright light and hot or peppery stimuli to the tongue and mouth. It is also linked with vomiting, coughing, and yawning.^[1] These reflex tears attempt to wash out irritants that may have come into contact with the eye.

The third category, in general, referred to as crying or weeping, is increased lacrimation due to strong emotional stress, anger, suffering, mourning, or physical pain. It does not occur during the brain's Fight-or-flight response because the sympathetic nervous system inhibits lacrimation. This practice is not restricted to negative emotions; many people cry when extremely happy. In humans, emotional tears can be accompanied by reddening of the face and sobbing — cough-like, convulsive breathing, sometimes involving spasms of the whole upper body. Tears brought about by emotions have a different chemical make-up than those for lubrication; emotional tears contain more of the protein-based hormones prolactin, adrenocorticotropic hormone, and leucine enkephalin (a natural painkiller) than basal or reflex tears. The limbic system is involved in production of basic emotional drives, such as anger, fear, etc. The limbic system, to be specific, the hypothalamus, also has a degree of control over the autonomic system. The parasympathetic branch of the autonomic nervous system controls the lacrimal glands via the neurotransmitter acetylcholine through both the nicotinic and muscarinic receptors. When these receptors are activated, the lacrimal gland is stimulated to produce tears.^[3]

^{TO BE CONTINUE................}